Glucocorticoids (GCs) are broadly prescribed for numerous pathological conditions because
of their anti-inflammatory, antiallergic and immunosuppressive effects, among other actions. …

Polychlorinated biphenyls (PCBs) are persistent environmental pollutants that can severely
disrupt the endocrine system. In the present study, early-weaned male rats were …

Why IVF pregnancy rates decline sharply after age 43 is unknown. In this study, we compared
granulosa cell (GC) function in young oocyte donors (nZ31, ages 21–29), middle-aged (…

Apoptosis plays an important role in the treatment of cancer, and targeting apoptosis-related
molecules in ovarian cancer (OC) is of great therapeutic value. Melatonin (Mel) is an …

Previous global RNA analysis was restricted to known transcripts in species with a defined
transcriptome. Next generation sequencing has transformed transcriptomics by making it …

The aim of this study was to understand whether high folic acid (HFA) exposure during the
perigestational period induces metabolic dysfunction in the offspring, later in life. To do this, …

Traumatic brain injury (TBI) is a major cause of preventable death and morbidity in young
adults. This complex condition is characterized by a significant blood–brain barrier leakage …

Growth plate injuries often result in undesirable bony repair causing bone growth defects,
for which the underlying mechanisms are unclear. Whilst the key importance of pro-angiogenic …

The oncogene MDM4, also known as MDMX or HDMX, contributes to cancer susceptibility
and progression through its capacity to negatively regulate a range of genes with …

Endogenous glucagon-like peptide-2 (GLP2) is a key mediator of refeeding-induced and
resection-induced intestinal adaptive growth. This study investigated the potential role of GLP2 …