Acoustic characterization of echogenic liposomes: Frequency-dependent attenuation and backscatter
Ultrasound contrast agents (UCAs) are used clinically to aid detection and diagnosis of
abnormal blood flow or perfusion. Characterization of UCAs can aid in the optimization of
ultrasound parameters for enhanced image contrast. In this study echogenic liposomes
(ELIPs) were characterized acoustically by measuring the frequency-dependent attenuation
and backscatter coefficients at frequencies between 3 and 30 MHz using a broadband pulse-
echo technique. The experimental methods were initially validated by comparing the …
abnormal blood flow or perfusion. Characterization of UCAs can aid in the optimization of
ultrasound parameters for enhanced image contrast. In this study echogenic liposomes
(ELIPs) were characterized acoustically by measuring the frequency-dependent attenuation
and backscatter coefficients at frequencies between 3 and 30 MHz using a broadband pulse-
echo technique. The experimental methods were initially validated by comparing the …
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