BACKGROUND: Waterpipe tobacco smoking usually involves heating flavored tobacco with
charcoal and inhaling the resulting smoke after it has passed through water. Waterpipe
tobacco smoking increases heart rate and produces subjective effects similar to those
reported by cigarette smokers. These responses are thought to be nicotine-mediated,
though no placebo-control studies exist. Accordingly, this double-blind, placebo-control
study compared the acute physiological and subjective effects of waterpipe tobacco smoking …