Administration of tranexamic acid after burr hole craniotomy reduced postoperative recurrence of chronic subdural hematoma in a Japanese regional population

A Miyakoshi, E Nakatani, H Kaneda, P Hawke… - …, 2023 - journals.lww.com
BACKGROUND: Although tranexamic acid (TXA) has occasionally been used to prevent
postoperative recurrence of chronic subdural hematoma (CSDH) after burr hole craniotomy
(BC), robust evidence of its efficacy has been lacking. OBJECTIVE: To assess the efficacy
and safety of postoperative oral administration of TXA after BC for CSDH among the elderly.
METHODS: This retrospective, propensity score–matched cohort study was carried out with
a large Japanese local population–based longitudinal cohort in the Shizuoka Kokuho …
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