The Mycobacterium bovis strain, bacille Calmette–Guérin (BCG) is one of the most widely
used human vaccines and remains one of the safest vaccines available. It has been used in
human populations for over 80 years and 100 million children receive the vaccine annually.
It has also been employed extensively for vaccine studies in laboratory animal hosts and is
currently being developed for use in a variety of livestock and wild animals. Despite the
large number of doses delivered since is first usage in 1921, reports of adverse reactions …

Purpose There are considerable variations in the number of adverse reaction reports related
to vaccine from different countries. The aim of this study was to review the development of
adverse reactions to bacille Calmette-Guérin (BCG) vaccination among hospitalized patients
in an Iranian referral hospital. Materials and Methods We identified hospitalized patients with
BCG complications in Pediatric Infectious Disease Research Center, Tehran University of
Medical Sciences, Tehran, Iran during January 2007-April 2009. Data on demographics …