Four new Daphniphyllum alkaloids, daphnilongeranins A− D (1− 4), along with four known
ones, daphniphylline, longistylumphylline A, deoxyisocalyciphylline B, and daphnicyclidin D,
were isolated from the leaves and stems of Daphniphyllum longeracemosum.
Daphnilongeranin A (1) is the first seco-10, 17-longistylumphylline A type Daphniphyllum
alkaloid, and daphnilongeranin B (2) is a new C-22 nor-Daphniphyllum alkaloid based on a
new C21 skeleton. Their structures and stereochemistry were determined using …

Four new Daphniphyllum alkaloids, daphnilongeranins AD (1-4), along with four known
ones, daphniphylline, longistylumphylline A, deoxyisocalyciphylline B, and daphnicyclidin D,
were isolated from the leaves and stems of Daphniphyllum longiracemosum.
Daphnilongeranin A (1) is the first seco-10, 17-longistylumphylline A type Daphniphyllum
alkaloid, and daphnilongeranin B (2) is a new C-22 nor-Daphniphyllum alkaloid based on a
new C21 skeleton. Their structures and stereochemistry were determined using …