[HTML][HTML] Allelic loss of the gene for the GPX1 selenium-containing protein is a common event in cancer
Y Hu, RV Benya, RE Carroll, AM Diamond - The Journal of nutrition, 2005 - Elsevier
Selenium has been shown to reduce cancer incidence in animal models and more recent
data indicate that it may be protective in humans as well. However, little is known about the
mechanism by which selenium prevents cancer. Cytosolic glutathione peroxidase (GPX1), a
selenium-containing antioxidant enzyme, has been implicated in the development of cancer
of the head and neck, lung, and breast, in part because of allelic loss at the GPX1 locus. The
study of allelic loss at the GPX1 locus in colon cancer was investigated by examining loss of …
data indicate that it may be protective in humans as well. However, little is known about the
mechanism by which selenium prevents cancer. Cytosolic glutathione peroxidase (GPX1), a
selenium-containing antioxidant enzyme, has been implicated in the development of cancer
of the head and neck, lung, and breast, in part because of allelic loss at the GPX1 locus. The
study of allelic loss at the GPX1 locus in colon cancer was investigated by examining loss of …
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