Non-invasive detection of fecal protein kinase C betaII and zeta messenger RNA: putative biomarkers for colon cancer.

LA Davidson, CM Aymond, YH Jiang… - …, 1998 - academic.oup.com
… determine if changes in fecal protein kinase C (PKC) expression … mRNA levels were altered
by the presence of a tumor, with tumor-… risk markers for human colon cancer are in progress. …

Evidence for a role of conventional protein kinase-Cα in the control of homotypic contacts and cell scattering of HT-29 human intestinal cells

M del Mont LLOSAS, E BATLLE, O COLL… - Biochemical …, 1996 - portlandpress.com
… We have investigated the involvement of different protein kinase C (PK-C) isoforms in these
… or TMTA did not alter the cellular distribution or the total levels of this enzyme (Figure 6C). …

The effect of CacyBP/SIP on the phosphorylation of ERK1/2 and p38 kinases in clear cell renal cell carcinoma

M Smereczańska, N Domian, G Młynarczyk… - International Journal of …, 2023 - mdpi.com
… CacyBP/SIP levels are altered in several cancers, indicating its … in colon or gastric tumors, it
is highly expressed, and the level … To date, 10 protein kinase inhibitors have been approved, …

[HTML][HTML] Effects of DCA on cell cycle proteins in colonocytes

YH Ha, DG Park - Journal of the Korean Society of Coloproctology, 2010 - ncbi.nlm.nih.gov
… cells, the expression of cyclin A was not changed or decreased … protein kinase C (PKC) and
mitogen-activated protein kinase (… colon cancer cell strain and the Caco-2 colon cancer cell …

Patterns of protein kinase C isoenzyme expression in transitional cell carcinoma of bladder: relation to degree of malignancy

L Langzam, R Koren, R Gal, V Kugel… - American journal of …, 2001 - academic.oup.com
… and diacylglycerol but not by Ca2+; and (3) atypical (zeta, lambda, iota) members of the
family, which differ in cystein-rich sequences and are not activated by Ca2+, phorbol esters, or …

Characterization of protein kinase C‐mediated phosphorylation of the short cytoplasmic domain isoform of C‐CAM

M Edlund, K Wikström, R Toomik, P Ek, B Öbrink - FEBS letters, 1998 - Wiley Online Library
C-CAM was first noted for its ability to mediate Ca 2+ -… growth of colon carcinoma cells in
syngeneic mice [10]. … of leukocytes leads to altered surface expression patterns of C-CAM [3]. …

Heterogeneity of protein kinase C β2 expression in lymphoid malignancies

…, D Buob, MC Copin, C Dumontet - …, 2007 - Wiley Online Library
… 2 levels have also been shown to be altered in other solid tumours, including colonic carcinoma
and … that loss of PKC β may decrease the rate of apoptosis in prostatic adenocarcinoma. …

Osmotic swelling-induced activation of the extracellular-signal-regulated protein kinases Erk-1 and Erk-2 in intestine 407 cells involves the Ras/Raf-signalling pathway

TD WIJK, J Dorrestijn, S NARUMIYA… - Biochemical …, 1998 - portlandpress.com
Human Intestine 407 cells respond to hypo-osmotic stress … pathway to be largely
independent of protein kinase C … replaced by Dulbecco’s modified Eagle’s medium containing …

Neurotensin-mediated activation of MAPK pathways and AP-1 binding in the human pancreatic cancer cell line, MIA PaCa-2

RA Ehlers, Y Zhang, MR Hellmich, BM Evers - Biochemical and biophysical …, 2000 - Elsevier
… (JNK) also known as stress-activated protein kinase (26, 27). … NT activates ERK in a human
colon cancer cell line, KM20, … Interestingly, intracellular Ca2 was not altered in this cell line …

Wnt5a is associated with cigarette smoke-related lung carcinogenesis via protein kinase C

YM Whang, U Jo, JS Sung, HJ Ju, HK Kim, KH Park… - PLoS …, 2013 - journals.plos.org
… to the development of smoking-related lung cancer. Protein kinase C (PKC) is a family of …
but phosphorylation of other isoforms of PKC were not changed (data not shown). In addition, …