The analysis of single-cell proteomes has recently become a viable complement to
transcriptomics and genomics studies. Proteins are the primary driver of cellular functionality
and mRNA levels are often an unreliable proxy of such. Therefore, the global analysis of the
proteome is essential to study cellular identities. Multiplexed and label-free mass
spectrometry-based approaches with single-cell resolution have lately attributed surprising
heterogeneity to presumed homogenous cell populations. Even though specialized …