Detoxification from drug abuse is strongly threatened by the occurrence of renewed
episodes of drug intake. In human addicts, relapse to drug seeking may take place even
after a considerably long period from the last drug consumption. Over the last decade, the
endocannabinoid system has received remarkable attention due to its unique features,
including its rewarding properties closely resembling those of the most commonly abused
substances and its multiple therapeutic implications. Although limited at present, evidence is …