[HTML][HTML] An exhaustive epistatic SNP association analysis on expanded Wellcome Trust data

C Lippert, J Listgarten, RI Davidson, J Baxter, H Poon… - Scientific reports, 2013 - nature.com
… -wide association analysis with improved power on the Wellcome Trust data consisting of …
We achieved improved power by expanding the control set to include other disease cohorts, …

[HTML][HTML] GWIS-model-free, fast and exhaustive search for epistatic interactions in case-control GWAS

B Goudey, D Rawlinson, Q Wang, F Shi, H Ferra… - BMC genomics, 2013 - Springer
exhaustive search through all SNP pairs in an entire GWAS, … exhaustive analysis of current
and near-future GWAS data. … sens/spec having increased |log 2 OR| and SNP pairs with low …

[PDF][PDF] GWIS-model-free, fast and exhaustive search for epistatic interactions in case-control GWAS

S From - 2013 - bmcgenomics.biomedcentral.com
… of exhaustive search through all SNP pairs in an entire GWAS, … exhaustive analysis of
current and near-future GWAS data. … the increased number of genotype calls for a pair of SNPs

Detecting epistasis in human complex traits

WH Wei, G Hemani, CS Haley - Nature Reviews Genetics, 2014 - nature.com
… single-sample genome-wide association studies (GWASs). If … in GWAS data through either
an exhaustive search of all SNP … searching for epistasis may confer increased statistical power …

Rapid epistatic mixed-model association studies by controlling multiple polygenic effects

D Wang, H Tang, JF Liu, S Xu, Q Zhang, C Ning - Bioinformatics, 2020 - academic.oup.com
… for exhaustive genome-wide epistatic association analysis by … simulated SNP pairs were
considered as true epistatic QTNs … number of significant SNP pairs increased with the increase …

A rapid epistatic mixed-model association analysis by linear retransformations of genomic estimated values

C Ning, D Wang, H Kang, R Mrode, L Zhou, S Xu… - …, 2018 - academic.oup.com
… when performing exhaustive epistatic association with the … We first estimate individuals’
epistatic effects by an extended … matrices for additive and epistatic SNP effects, respectively. …

High-performance computing to detect epistasis in genome scale data sets

A Upton, O Trelles, JA Cornejo-García… - Briefings in …, 2016 - academic.oup.com
epistasis, by considering the association of multiple SNP … a reduced 89 294-SNP data set
took 14 days to complete [ 9 ]. … The analysis of an expanded Wellcome Trust data set deployed …

Genome-wide marginal epistatic association mapping in case-control studies

L Crawford, X Zhou - bioRxiv, 2018 - biorxiv.org
… the first order Taylor series expansion is an approximation to a … marginal epistatic detection
in the PLINK exhaustive searches … , we first rank SNPs according to their marginal epistatic p-…

Immunochip analyses of epistasis in rheumatoid arthritis confirm multiple interactions within MHC and suggest novel non-MHC epistatic signals

WH Wei, CY Loh, J Worthington, S Eyre - The Journal of rheumatology, 2016 - jrheum.org
… We performed an exhaustive pairwise search for epistatic … replicated if both epistatic SNP
had genotype data available and with p … of increased samples and high density SNP offered by …

A Framework for Accessible Cluster-Enabled Epistatic Analysis

A Upton, J Karlsson, O Trelles, M Hernandez… - Euro-Par 2016: Parallel …, 2017 - Springer
… polymorphism (SNP) interactions, epistatic interactions, … As a result, the exhaustive search
for epistasis can be … The increased usage of epistatic analysis has the potential to provide …