Electrosynthesis is a powerful method to functionalise organic molecules without the need to
use chemical reagents or protecting groups, yet it is not widely used in synthesis. In this
study, we investigated the Shono oxidation of a tertiary amide (electrochemical
functionalisation of a C–H bond adjacent to an amide nitrogen atom), demonstrating the
value of performing cyclic voltammetry, varying voltage and charge per mole, selection of
electrolyte and electrode material. We demystify the process to demonstrate a simple …