An important consequence of the COVID-19 health crisis has been the suspension of face-to-face teaching activity in all teaching levels from mid-March of the academic year 2019–2020. In this sense, changes in Complutense University of Madrid toward an e-learning methodology have been made. In this work, we describe the adaptation to an online teaching model of two degree analytical chemistry courses: Pharmacy and Food Science and Technology. A mixed model has been performed for classes, using both online synchronous and asynchronous learning. The opinion of the students about this adaptation was evaluated. Although students preferred to carry out a face-to-face teaching and learning process, they found certain advantages in the online teaching modality, such as “Save time” and “Schedule flexibility”.