过去一年中添加的文章,按日期排序

Exploring the efficacy of cannabinoids in the management of multiple sclerosis

A Rykucka, N Zozula, M Wąs, J Kiełbasa… - Journal of Education …, 2024 - apcz.umk.pl
5 天前 - … In studies utilizing an animal model of MS, the non-selective … potential of cannabinoids
in animal models of MS. … the potential efficacy, safety, and limitations of this medication. …

[PDF][PDF] From Protein Misfolding to Dementia: Basic Research, Innovative Diagnosis and Early Biomarkers

MB Bacınoğlu, A Ciullini, G Giaccone… - Frontiers in Bioscience …, 2024 - article.imrpress.com
6 天前 - … platelet tau levels as a potential diagnostic approach. In the … diagnostic purposes,
animal models are crucial to enhance … and disadvantages of each model. Specifically, the au…

Oligodendrocyte precursor cell-derived exosomes combined with cell therapy promote clinical recovery by immunomodulation and gliosis attenuation

SIP Santos, SJO Peñuela, A de Paula Filho… - Frontiers in Cellular … - frontiersin.org
14 天前 - Multiple sclerosis is a chronic inflammatory disease of the … ) have already
demonstrated their potential in neuronal … (OPCs) in an animal model of multiple sclerosis. OPCs …

The connection between gut microbiota and its metabolites with neurodegenerative diseases in humans

JP Fabi - Metabolic Brain Disease, 2024 - Springer
20 天前 - … observations and animal models experimentation. This paper … Multiple Sclerosis
(MS) is a chronic immune-mediated … potential in inflammatory bowel disease (IBD), multiple

[PDF][PDF] Stem Cell Therapies for Multiple Sclerosis: Promising Approaches and Future Directions. Trends Int Med. 2024; 3 (1): 1-6

E Lerner, VS Gallicchio - … : Dr. Vincent S. Gallicchio, Department of … - scivisionpub.com
26 天前 - … , they often have limitations such as incomplete efficacy and … demonstrated the
safety and potential efficacy of MSCs and … , there is no single animal model that can capture all …

A novel in vitro model for investigating oligodendroglial maturation and myelin deposition under demyelinating and remyelinating conditions: Impact of microglial …

AA Di Pietro, LA Pasquini - Molecular and Cellular Neuroscience, 2024 - Elsevier
34 天前 - … Experimental models of multiple sclerosis (MS) have … Various in vivo animal models
have successfully replicated key … model shows significant potential in assessing potential

ALLOGENEIC CD19 CAR EBV T CELLS FOR THE TREATMENT OF B-CELL DRIVEN AUTOIMMUNE DISEASES

A Brito, A Habibi, S Cha, M Charbonneau, P Foubert… - Cytotherapy, 2024 - Elsevier
36 天前 - … (SLE) existing therapies have limitations due to their … viral antigen specificity to help
limit potential off-target toxicity. In … targets from patients with SLE and multiple sclerosis (MS). …

Discovery of a brain penetrant small molecule antagonist targeting LPA1 receptors to reduce neuroinflammation and promote remyelination in multiple sclerosis

MM Poon, KI Lorrain, KJ Stebbins, GC Edu… - Scientific Reports, 2024 - nature.com
50 天前 - … on immunosuppression to limit inflammation and further … in the MOG-EAE mouse
model of multiple sclerosis. (A) … conductance, we utilized visual evoked potentials (VEPs), a …

A Systematic Review of Semaglutide's Influence on Cognitive Function in Preclinical Animal Models and Cell-Line Studies

RO Tipa, DG Balan, MT Georgescu, LA Ignat… - International Journal of …, 2024 - mdpi.com
56 天前 - … While promising, limitations include fewer studies, … (EAE)-induced multiple sclerosis
(MS) in mice. The EAE … of semaglutide’s potential effects on animal models and cell lines in …

Investigation of Novel Variants in Familial Multiple Sclerosis Through Family-based Association Tests and Segregation Analyses (S17. 007)

A Siva, A Bulbul, E Everest, M Tutuncu, U Uygunoglu… - Neurology, 2024 - AAN Enterprises
78 天前 - … , which were supported by functional evidence, mouse models, and expression
patterns in the … , providing insights into potential pathogenic implications in familial MS cohorts. …