Antifungal drugs: New insights in research & development

AM Nicola, P Albuquerque, HC Paes… - Pharmacology & …, 2019 - Elsevier
… of these drugs fail to reach the patients. In this review, we discuss the development of
antifungal drugs focusing on the approach of drug repurposing and the search for novel drugs for …

Antifungals discovery: an insight into new strategies to combat antifungal resistance

AM Fuentefria, B Pippi, DF Dalla Lana… - Letters in applied …, 2018 - academic.oup.com
… The systematic research in the … on new strategies in the discovery of antifungal agents (natural
from plants, synthetic and semisynthetic compounds). The review was limited to studies

Avenues for antifungal drug discovery and development: where to now?

S Vassilopoulos, E Mylonakis - Expert Opinion on Drug Discovery, 2022 - Taylor & Francis
… In addition to studies that evaluate new antifungal agents as single agents, clinical trials
assess drug candidates as part of treatment along with the current standard of care. For example…

Current insights on antifungal therapy: Novel nanotechnology approaches for drug delivery systems and new drugs from natural sources

F Sousa, D Ferreira, S Reis, P Costa - Pharmaceuticals, 2020 - mdpi.com
… It is important to add that resistance is a cross-cutting issue to all of the currently available
classes of antifungal agents, therefore overcoming antifungal resistance can be considered as …

Current antimycotics, new prospects, and future approaches to antifungal therapy

G Wall, JL Lopez-Ribot - Antibiotics, 2020 - mdpi.com
… can be exploited for antifungal drug development. This has also resulted in a very restricted
number of antifungal drugs that are clinically available for the treatment of invasive fungal …

[HTML][HTML] Antifungal drug discovery: new theories and new therapies

CJ Seneviratne, EAR Rosa - Frontiers in microbiology, 2016 - frontiersin.org
… Hence, the development of more effective and safe antifungal agents is a top priority in the
research topic aimed to address the new theories and therapies pertaining to antifungal drug

An insight into new strategies to combat antifungal drug resistance

YH Zheng, YY Ma, Y Ding, XQ Chen… - Drug design …, 2018 - Taylor & Francis
understanding of mechanisms of drug resistance contributes to searching for new targets and
developing new antifungal … some potential targets to overcome antifungal drug resistance. …

Novel avenues for identification of new antifungal drugs and current challenges

J Jampilek - Expert Opinion on Drug Discovery, 2022 - Taylor & Francis
… of new antifungal drugs, provides an overview of the most important molecules in terms of
basic (laboratory) research and compounds currently in clinical trials, and focuses on drug

Antifungal drugs: the current armamentarium and development of new agents

N Robbins, GD Wright, LE Cowen - Microbiology spectrum, 2016 - Am Soc Microbiol
… of antifungal agents and the most promising emerging therapies in the antifungal development
… Here we highlight some of the most promising new antifungal drug targets currently being …

[HTML][HTML] New insights into the mechanism of antifungal action of 8-hydroxyquinolines

B Pippi, W Lopes, P Reginatto, FÉK Silva… - Saudi pharmaceutical …, 2019 - Elsevier
… represent valid ways of seeking new antifungal agents, our research aimed to gain information
about the mode of action in order to rationalize the design of new antifungal derivatives. …