Antimicrobial activity and safety applications of meso-tetra (4-pyridyl) platinum (II) porphyrin

LQS Lopes, AP Ramos, PM Copetti, TV Acunha… - Microbial …, 2019 - Elsevier
Tetra-platinated (II) porphyrin hexafluorophosphate compound (4-PtTPyPor) was
synthetized and along 5, 10, 15, 20-tetrakis (4-pyridyl) porphyrin (4-TPyPor), evaluated
about the antimicrobial activity and safety. The effect was evaluated with and without light
exposition. The antimicrobial activity was analyzed by microdilution and growth curve
method. The assays showed an increase of antimicrobial potential caused by porphyrins
with light exposition comparing the treatment without light irradiation. The biocompatibility …
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