Antimicrobial and cytotoxic effects of the Copaifera reticulata oleoresin and its main diterpene acids

ALP Barbosa, A Wenzel-Storjohann, JD Barbosa… - Journal of …, 2019 - Elsevier
Ethnopharmacological relevance The oleoresin of Brazilian Copaifera reticulata is a
traditional remedy used for the treatment of skin and urinary tract infections, respiratory
diseases, rheumatism, ulcer and tumours; thus, playing an important role in the primary
health care of the indigenous population. Aim As most previous pharmacological tests used
the crude oleoresin and only a few studies so far dealt with enriched fractions or pure
chemically defined compounds, the aim of this study was to systematically evaluate the …

[PDF][PDF] Antimicrobial and cytotoxic effects of the Copaifera reticulata oleoresin and its main diterpene acids 2

ALP Barbosaa, A Wenzel-Storjohannc, JD Barbosad… - academia.edu
Aim: As most previous pharmacological tests used the crude oleoresin and only a few
studies 7 so far dealt with enriched fractions or pure chemically defined compounds, the aim
of this study 8 was to systematically evaluate the antimicrobial and cytotoxic properties of the
Copaifera 9 reticulata oleoresin and to assign traditional uses to specific secondary
metabolites. 10 Materials and methods: The oleoresin, as well as its neutral and acidic
fractions were tested for 11 their activity against six cancer cell lines, two clinically relevant …
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