Atypical antipsychotic agents: a critical review

JA Worrel, PA Marken, SE Beckman… - American Journal of …, 2000 - academic.oup.com
… antipsychotic agents when used to treat schizophrenia and other disorders are reviewed.
Atypical antipsychotic agents were developed in response to problems with typical agents, …

Antipsychotic agents differ in how fast they come off the dopamine D2 receptors. Implications for atypical antipsychotic action.

S Kapur, P Seeman - Journal of Psychiatry and Neuroscience, 2000 - ncbi.nlm.nih.gov
… (K,) of antipsychotic agents for the D2 receptors, with particular reference to typical and …
antipsychotic agents. Design: The k. of several typical as well as atypical antipsychotic agents (…

Antipsychotic agents

FJ Vinick, JH Heym - Annual Reports in Medicinal Chemistry, 1987 - Elsevier
Publisher Summary The organic pathology underlying chronic schizophrenia, which remains
a devastating mental disorder, has emerged as a major topic of discussion. It presents an …

The pharmacology and toxicology of atypical antipsychotic agents

MJ Burns - Journal of Toxicology: Clinical Toxicology, 2001 - Taylor & Francis
… The need for antipsychotic agents with improved efficacy and side effect profiles has led
to the development of atypical antipsychotic agents Since 1990, four atypical antipsychotics

Antipsychotic agents and QT changes.

R Welch, P Chue - Journal of Psychiatry and Neuroscience, 2000 - ncbi.nlm.nih.gov
… conventional antipsychotics are significantly more cardiotoxic, particularly agents in the …
antipsychotic medications are not available to patientsin North America. Yet, conventional …

Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors

BL Roth, SC Craigo, MS Choudhary… - … of Pharmacology and …, 1994 - cdr.lib.unc.edu
antipsychotic agents tested for the 5-HT7 receptor (Ki= 0.5 nM). Three putative atypical
antipsychotic agents … Several dopamine-selective antipsychotic agents (raclopride, rimcazole and …

Clozapine: a novel antipsychotic agent

RJ Baldessarini, FR Frankenburg - New England Journal of …, 1991 - Mass Medical Soc
antipsychotic agents to have few of the extrapyramidal side effects typical of nearly all the
antipsychotic (neuroleptic) agents … the first tricyclic antipsychotic agent and the dibenzazepine …

Side effect profiles of new antipsychotic agents.

DE Casey - The Journal of clinical psychiatry, 1996 - europepmc.org
… management challenges posed by existing antipsychotic drug therapy. Considerable progress
… Overall, these new antipsychotic agents greatly improve the treatment of psychosis by …

Depression in schizophrenia: perspective in the era of “atypical” antipsychotic agents

SG Siris - American Journal of Psychiatry, 2000 - Am Psychiatric Assoc
… the advent of atypical antipsychotic agents can be understood in … should be treated with
antipsychotic agents and which with … by the advent of the so-called atypical antipsychotic agents. …

The case for long‐acting antipsychotic agents in the post‐CATIE era

HA Nasrallah - Acta Psychiatrica Scandinavica, 2007 - Wiley Online Library
Antipsychotic agents are the major class of drugs used in the treatment of … The atypical
antipsychotics represent an improvement in both efficacy and tolerability over conventional agents