Antitubercular nanocarrier monotherapy: Study of In Vivo efficacy and pharmacokinetics for rifampicin

J Trousil, O Pavliš, P Kubíčková, M Škorič… - Journal of Controlled …, 2020 - Elsevier
Tuberculosis represents a major global health problem for which improved approaches are
needed to shorten the course of treatment and to combat the emergence of resistant strains.
The development of effective and safe nanobead-based interventions can be particularly
relevant for increasing the concentrations of antitubercular agents within the infected site
and reducing the concentrations in the general circulation, thereby avoiding off-target toxic
effects. In this work, rifampicin, a first-line antitubercular agent, was encapsulated into …

[引用][C] Antitubercular nanocarrier monotherapy: Study of

J Trousil, O Pavliš, P Kubíčková, M Škorič, V Marešová… - vivo
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