… we include in this review the antitumor compound lissoclinolide (Figure 3) isolated from
the marine ascidian Lissoclinum patella [59]. This compound was originally isolated from a …

… The third antitumor compound from our laboratory currently in clinical trial is Ecteinascidin
743 (ET 743). The antitumor activity of extracts of the tunicate Ecteinascidia turbinata were first …

… , four of which are tin compounds [17]. Despite this, the exact mechanism of anti-tumor action
of organotin compounds remains unknown. Tin compounds and their therapeutic potentials …

… (IV) antitumor compounds are reduced in vivo. Both cis-Pt(II) and cis-Pt(IV) compounds are
antitumoral … the DNA lesions formed by Pt(IV) compounds and their Pt(II) analogues may have …

… We will review the compounds with antitumor potential identified so far in mushrooms, including
… and compounds extracted from mushrooms which have potential antitumor properties. …

… which suggested that their antitumor properties were due to … The main deficiency of these
compounds is their cytotoxicity … At present, we are preparing mainly new compounds by …

… Abstract: The discovery of new compounds with antitumoral activity has become one of the
… act as antitumoral agents, including groove binders, alkylating and intercalator compounds. …

… and non-classical) compounds has been found [13]; these compounds will not be discussed
… compounds with antitumor activity are depicted in Fig. 5. Whether or not these compounds …

… the trcins geometrical isomers of these compounds are ineffective (I, 2). It was … compounds,
whose structures are given in Fig. 1, introduced an entirely new elass of antitumor compounds…

… This review analyzed the antitumor compounds obtained only from Mediterranean ascidian.
The aim was to focus on Mediterranean biodiversity of these species because this area is …