Antiviral indolosesquiterpenoid xiamycins C–E from a halophilic actinomycete
New metabolites, xiamycins C–E (1–3), were isolated from a Streptomyces. sp (# HK18)
culture inhabiting the topsoil in a Korean solar saltern. The planar structures of the xiamycins
C–E were elucidated as carbazole-bearing indolosesquiterpenoids using a combined
analysis of NMR, MS, UV, and IR spectroscopic data. The absolute configurations of these
new compounds were determined by analyses of NOESY and ECD data. When the
xiamycins were tested for inhibitory activity on porcine epidemic diarrhea virus (PEDV) …
culture inhabiting the topsoil in a Korean solar saltern. The planar structures of the xiamycins
C–E were elucidated as carbazole-bearing indolosesquiterpenoids using a combined
analysis of NMR, MS, UV, and IR spectroscopic data. The absolute configurations of these
new compounds were determined by analyses of NOESY and ECD data. When the
xiamycins were tested for inhibitory activity on porcine epidemic diarrhea virus (PEDV) …
[引用][C] Antiviral Indolosesquiterpenoid Xiamycins C–E from a Halophilic Actinomycete
K Seong-Hwan, H Thi-Kim-Quy, OW Keun, S Jongheon… - 2016
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