过去一年中添加的文章,按日期排序

MicroRNA-195-5p Attenuates Intracerebral-Hemorrhage-Induced Brain Damage by Inhibiting MMP-9/MMP-2 Expression

YC Tsai, CH Chang, YB Chong, CH Wu, HP Tsai… - Biomedicines, 2024 - mdpi.com
4 天前 - … anti-apoptotic effects of miR-195-5p, demonstrated through TUNEL assays, further
underscore its therapeutic promise in addressing the secondary brain injury and apoptosis

Potential role and therapeutic implications of glutathione peroxidase 4 in the treatment of Alzheimer's disease

Y Shen, G Zhang, C Wei, P Zhao, Y Wang… - Neural Regeneration …, 2025 - journals.lww.com
6 天前 - … ’s disease brain, resulting in oxidative stress, inflammation, ferroptosis, and apoptosis,
which are closely associated with pathological damage in Alzheimer’s disease. Several …

Apigenin: A Bioflavonoid with a Promising Role in Disease Prevention and Treatment

KS Allemailem, A Almatroudi, HOA Alharbi… - Biomedicines, 2024 - mdpi.com
6 天前 - … This could be due to its ability to reduce oxidative stress and inhibit hyperactive
autophagy and apoptosis [44]. The study observed that when osteoblastic cells were treated

Metabolic Shift and Increased Osmotic Pressure Underlie Age-Related Macular Degeneration: A Review

L Schwartz, J Schwartz, M Hnery, A Bakkar - 2024 - preprints.org
7 天前 - … In AD or AMD, there is prominent apoptotic cell death. These diseases are different
entities but share multiple common epidemiological and biological features [1–3]. Cancer …

MicroRNA-15b promotes cardiac ischemia injury by the inhibition of Mitofusin 2/PERK pathway

W Zhang, M Zhang, J Ma, Y Yao, Y Jiang, Q Huo… - Biochemical …, 2024 - Elsevier
9 天前 - … mitochondrial dysfunction, and cardiac apoptosis eventually. In conclusion, …
apoptosis and elucidated that pro-apoptotic miR-15b plays crucial roles during the pathogenesis of …

Metabolic profiling of Vitex Pubescens Vahl bark via UPLC-ESI-QTOF/MS/MS analysis and evaluation of its antioxidant and acetylcholinesterase inhibitory activities

S Abdelbaset, IM Ayoub, OG Mohamed… - … Medicine and Therapies, 2024 - Springer
9 天前 - … The pathogenesis of Alzheimer’s disease incidence is complex and involves various
… of β-amyloid plaques, neuroinflammation, oxidative stress, and apoptosis. Conventional …

Parathyroid hormone (1–34) retards the lumbar facet joint degeneration and activates Wnt/β-catenin signaling pathway in ovariectomized rats

Y Gou, H Li, X Sun, D Chen, F Tian - Journal of Orthopaedic Surgery and …, 2024 - Springer
9 天前 - … chondrocytes by inhibiting cell apoptosis and increasing their number. Hormone
therapy seems to be a promising approach for treating diseases caused by estrogen deficiency…

Ferroptosis: A Novel Mechanism of Cell Death in Ophthalmic Conditions

Y Yang, Y Lin, H Zhongyu, B Wang, W Zheng… - Frontiers in … - frontiersin.org
10 天前 - … Our review of the current research on ferroptosis in ophthalmic diseases reveals
significant advancements in our understanding of the pathogenesis, aetiology, and treatment of …

Human trophoblast invasion and migration are mediated by the YAP1-CCN1 pathway: defective signaling in trophoblasts during early-onset severe preeclampsia

L Wu, S Wang, H Li, H Lu, Y Zheng… - Biology of …, 2024 - academic.oup.com
10 天前 - … but not apoptosis, and decreased placental expression of YAP1 and CCN1 in
pregnancies complicated by early-onset sPE might contribute to the pathogenesis of this disease. …

Melatonin ameliorates Slc26a2-associated chondrodysplasias by attenuating endoplasmic reticulum stress and apoptosis of chondrocytes

P Li, C Zheng, J Hu, W Lu, D Wang, X Hao, C Zhao… - … & Diseases, 2024 - Elsevier
10 天前 - … for chondrocyte apoptosis.Hence, we assessed the expression of CHOP and the
apoptotic … Remarkably, melatonin treatment 378 decreased the percentage of chondrocytes …