过去一年中添加的文章,按日期排序

AB1190 EVALUATION OF THE CORRELATION OF PARK-7 EXPRESSION WITH CLINICAL PARAMETERS IN PATIENTS WITH SYSTEMIC SCLEROSIS

E Ozturk, DB Gökten, R Mercan - 2024 - ard.bmj.com
27 天前 - … and without treatment, could significantly contribute to a comprehensive understanding
of the role of PARK-7 in the pathogenesis and its potential applicability in treatment. It is …

[HTML][HTML] Targeting ferroptosis using Chinese herbal compounds to treat respiratory diseases

M Xu, D Zhang, J Yan - Phytomedicine, 2024 - Elsevier
27 天前 - … Compared with the use of apoptosis and necroptosis inhibitors, the above
changes were significantly improved after treatment with ferroptosis inhibitors, indicating that …

METTL3 deficiency leads to ovarian insufficiency due to IL-1β overexpression in theca cells

M Cao, C Yuan, X Chen, G He, T Chen, J Zong… - Free Radical Biology …, 2024 - Elsevier
28 天前 - … These cellular events ultimately led to granulosa cell apoptosis and a decrease
in oestradiol synthesis, resulting in POI development. Collectively, these findings reveal how …

Disease Types and Pathogenic Mechanisms Induced by Pm2. 5 in Five Human Systems: An Analysis Using Omics and Human Disease Databases

Z Zhang, X Li, J Wenger, X Long, Z Bao, X Qi, Y Han… - papers.ssrn.com
29 天前 - … types and pathogenic mechanisms induced by PM2.5 in … In this study, the disease
types induced by PM2.5 in the … pathogenic mechanisms identified at molecular level. The …

Psychological stressors involved in the pathogenesis of premature ovarian insufficiency and potential intervention measures

YP Xu, JC Fu, ZL Hong, DF Zeng, CQ Guo… - Gynecological …, 2024 - Taylor & Francis
29 天前 - … follicular growth/atresia by regulating the apoptosis of germ cells and somatic cells.
In the ovary of depression-like mice, more GCs apoptosis occurs and the expression of Bcl2 …

[PDF][PDF] A Serine Protease Inhibitor, Camostat Mesilate, Suppresses Urinary Plasmin Activity and Alleviates Hypertension and Podocyte Injury in Dahl Salt-Sensitive …

岩田康伸, イワタヤスノブ - kumadai.repo.nii.ac.jp
29 天前 - In proteinuric renal diseases, the serine protease (SP) plasmin activates the epithelial
sodium channel (ENaC) by cleaving its γ subunit. We previously demonstrated that a high…

Neuroinflammation: From Molecular Basis to Therapy

I Zanella - International Journal of Molecular Sciences, 2024 - mdpi.com
30 天前 - Neuroinflammatory conditions in the central nervous system (CNS) are implicated
in the pathogenesis of several neuroimmune disorders such as acquired demyelinating …

Unveiling the Nexus of CD38 Overactivation, NAD+ Depletion, and Mitochondrial Dysfunction in Immunological Failure Among Virologically Suppressed HIV Patients

ML Gnoni - Norton Healthcare Medical Journal, 2024 - nortonhealthcaremedicaljournal …
30 天前 - Introduction With the advent of antiretroviral therapy (ART), HIV has become a
manageable chronic disease. Despite effective virologic suppression, approximately 30% of …

Ginseng total saponin improves red blood cell oxidative stress injury by regulating tyrosine phosphorylation and glycolysis in red blood cells

Y Zhao, Y Cui, W Ni, S Yu, D Pan, S Liu, Z Jia, Y Gao… - Phytomedicine, 2024 - Elsevier
31 天前 - … Oxidative stress is the main cause of many diseases, but because of its complex
pathogenic factors, there is no clear method for treating it. Ginseng total saponin (GTS) an …

Drug-Resistant Epithelial Ovarian Cancer: Current and Future Perspectives

M Mehrotra, P Phadte, P Shenoy, S Chakraborty… - Cell and Molecular …, 2024 - Springer
31 天前 - … , metabolism, apoptosis evasion, cancer stem cells, and autophagy, which play
pivotal roles in mediating resistance and disease relapse in EOC. Beyond standard treatments, …