Asiaticoside, a component of Centella asiatica attenuates RANKL‐induced osteoclastogenesis via NFATc1 and NF‐κB signaling pathways
L He, G Hong, L Zhou, J Zhang, J Fang… - Journal of cellular …, 2019 - Wiley Online Library
Identification of natural compounds that inhibit osteoclastogenesis will facilitate the
development of antiresorptive treatment of osteolytic bone diseases. Asiaticoside is a
triterpenoid derivative isolated from Centella asiatica, which exhibits varying biological
effects like angiogenesis, anti‐inflammation, wound healing, and osteogenic differentiation.
However, its role in osteoclastogenesis remains unknown. Here, we show that Asiaticoside
can suppress RANKL‐induced osteoclast formation and bone resorption in a dose …
development of antiresorptive treatment of osteolytic bone diseases. Asiaticoside is a
triterpenoid derivative isolated from Centella asiatica, which exhibits varying biological
effects like angiogenesis, anti‐inflammation, wound healing, and osteogenic differentiation.
However, its role in osteoclastogenesis remains unknown. Here, we show that Asiaticoside
can suppress RANKL‐induced osteoclast formation and bone resorption in a dose …
Asiaticoside, a component of Centella asiatica attenuates RANKL-induced osteoclastogenesis via NFATc1 and NF-κB signaling pathways.
HLL He LiLei, HGJ Hong GuoJu, ZL Zhou Lin… - 2019 - cabidigitallibrary.org
Identification of natural compounds that inhibit osteoclastogenesis will facilitate the
development of antiresorptive treatment of osteolytic bone diseases. Asiaticoside is a
triterpenoid derivative isolated from Centella asiatica, which exhibits varying biological
effects like angiogenesis, anti-inflammation, wound healing, and osteogenic differentiation.
However, its role in osteoclastogenesis remains unknown. Here, we show that Asiaticoside
can suppress RANKL-induced osteoclast formation and bone resorption in a dose …
development of antiresorptive treatment of osteolytic bone diseases. Asiaticoside is a
triterpenoid derivative isolated from Centella asiatica, which exhibits varying biological
effects like angiogenesis, anti-inflammation, wound healing, and osteogenic differentiation.
However, its role in osteoclastogenesis remains unknown. Here, we show that Asiaticoside
can suppress RANKL-induced osteoclast formation and bone resorption in a dose …
以上显示的是最相近的搜索结果。 查看全部搜索结果