Objective: Isotonic saline is the most commonly used crystalloid in the ICU, but recent
evidence suggests that balanced fluids like Lactated Ringer's solution may be preferable.
We examined the association between choice of crystalloids and in-hospital mortality during
the resuscitation of critically ill adults with sepsis. Design: A retrospective cohort study of
patients admitted with sepsis, not undergoing any surgical procedures, and treated in an
ICU by hospital day 2. We used propensity score matching to control for confounding and …

OBJECTIVE: Isotonic saline is the most commonly used crystalloid in the ICU, but recent
evidence suggests that balanced fluids like Lactated Ringer's solution may be preferable.
We examined the association between choice of crystalloids and in-hospital mortality during
the resuscitation of critically ill adults with sepsis. DESIGN: A retrospective cohort study of
patients admitted with sepsis, not undergoing any surgical procedures, and treated in an
ICU by hospital day 2. We used propensity score matching to control for confounding and …