Association of HTLV-1 infection prevalence with TLR7 single nucleotide polymorphisms (rs179008 & rs179009) in asymptomatic blood donors in Khorasan Province …

HM Habibabadi, M Parsania, AA Pourfathollah… - Gene Reports, 2022 - Elsevier
Background Human T-lymphotropic virus type 1 (HTLV-1) cause two diseases in humans
such as adult T-cell leukemia/lymphoma (ATL) and HTLV-1 associated myelopathy/tropical
spastic paraparesis (HAM/TSP). About, 15–20 million persons are infected with HTLV-1 in
worldwide. Single nucleotide polymorphisms (SNPs) are a genetic variation that occurs in>
1% of the general population; they can alter promoter activities, gene expression, mRNA
stability, and protein structure and function. Our aim in this study was to investigate the …
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