Association of early pregnancy perfluoroalkyl and polyfluoroalkyl substance exposure with birth outcomes
Importance Prenatal perfluoroalkyl and polyfluoroalkyl substances (PFAS) have been linked
to adverse birth outcomes. Previous research showed that higher folate concentrations are
associated with lower blood PFAS concentrations in adolescents and adults. Further studies
are needed to explore whether prenatal folate status mitigates PFAS-related adverse birth
outcomes. Objective To examine whether prenatal folate status modifies the negative
associations between pregnancy PFAS concentrations, birth weight, and gestational age …
to adverse birth outcomes. Previous research showed that higher folate concentrations are
associated with lower blood PFAS concentrations in adolescents and adults. Further studies
are needed to explore whether prenatal folate status mitigates PFAS-related adverse birth
outcomes. Objective To examine whether prenatal folate status modifies the negative
associations between pregnancy PFAS concentrations, birth weight, and gestational age …