Association of rare copy number variants with risk of depression
Importance The role of large, rare copy number variants (CNVs) in neuropsychiatric
disorders is well established, but their association with common psychiatric disorders, such
as depression, remains unclear. Objective To examine the association of a group of 53
CNVs associated with neurodevelopmental disorders and burden of rare CNVs with risk of
depression. Design, Setting, and Participants This case-control study used data from the UK
Biobank study sample, which comprised 502 534 individuals living in the United Kingdom …
disorders is well established, but their association with common psychiatric disorders, such
as depression, remains unclear. Objective To examine the association of a group of 53
CNVs associated with neurodevelopmental disorders and burden of rare CNVs with risk of
depression. Design, Setting, and Participants This case-control study used data from the UK
Biobank study sample, which comprised 502 534 individuals living in the United Kingdom …
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