Associations of impaired behaviors with elevated plasma chemokines in autism spectrum disorders
P Ashwood, P Krakowiak, I Hertz-Picciotto… - Journal of …, 2011 - Elsevier
A role for immune dysfunction has been suggested in autism spectrum disorders (ASD).
Elevated levels of chemokines have been detected in the brain and CSF of individuals with
ASD but, to date, no study has examined chemokine levels in the plasma of children with
this disorder. In the current study, we determined whether there were differential profiles of
chemokines in the plasma of children with ASD compared to age-matched typically
developing controls and children with developmental disabilities other than ASD. Increased …
Elevated levels of chemokines have been detected in the brain and CSF of individuals with
ASD but, to date, no study has examined chemokine levels in the plasma of children with
this disorder. In the current study, we determined whether there were differential profiles of
chemokines in the plasma of children with ASD compared to age-matched typically
developing controls and children with developmental disabilities other than ASD. Increased …
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