Asymmetric Synthesis of Halocyclized Products by Using Various Catalysts: A State‐of‐the‐Art Review

S De, A Kumar Dan, R Sahu… - European Journal of …, 2022 - Wiley Online Library
European Journal of Organic Chemistry, 2022Wiley Online Library
Halogens play a crucial part in synthetic organic chemistry. Halo‐cyclized products hold
numerous applications in the pharmaceutical industries, agrochemicals, natural product
synthesis, and material chemistry. Thus, this review will discuss the role of various catalysts,
such as from metal‐catalysts to organocatalysts, under different conditions to synthesize
various halocyclized products. The synthesis and catalytic mechanisms underlying the
different asymmetric transformations will also be covered by emphasizing the …
Abstract
Halogens play a crucial part in synthetic organic chemistry. Halo‐cyclized products hold numerous applications in the pharmaceutical industries, agrochemicals, natural product synthesis, and material chemistry. Thus, this review will discuss the role of various catalysts, such as from metal‐catalysts to organocatalysts, under different conditions to synthesize various halocyclized products. The synthesis and catalytic mechanisms underlying the different asymmetric transformations will also be covered by emphasizing the enantioselectivities, diastereoselectivities, and regioselectivities from the existing pieces of literature.
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