Background Oxidative stress is one of the major mechanism involved in pathogenesis of
myocardial infarction. Use of natural products as therapeutic approach for ischemic
myocardial injury is gaining attention worldwide. Purpose This study was designed to
investigate efficacy of Narirutin rich fraction (NRF), obtained from grape fruit peel, in the
treatment of isoproterenol induced myocardial infarction in rats. Methods After 3-days
pretreatment with NRF (100 mg/kg and 200 mg/kg, po) myocardial injury was induced by …

Background: Oxidative stress is one of the major mechanism involved in pathogenesis of
myocardial infarction. Use of natural products as therapeutic approach for ischemic
myocardial injury is gaining attention worldwide. Purpose: This study was designed to
investigate efficacy of Narirutin rich fraction (NRF), obtained from grape fruit peel, in the
treatment of isoproterenol induced myocardial infarction in rats. Methods: After 3-days
pretreatment with NRF (100 mg/kg and 200 mg/kg, po) myocardial injury was induced by …