Attributable mortality of acute respiratory distress syndrome: a systematic review, meta-analysis and survival analysis using targeted minimum loss-based estimation

LK Torres, KL Hoffman, C Oromendia, I Diaz… - Thorax, 2021 - thorax.bmj.com
Background Although acute respiratory distress syndrome (ARDS) is associated with high
mortality, its direct causal link with death is unclear. Clarifying this link is important to justify
costly research on prevention of ARDS. Objective To estimate the attributable mortality, if
any, of ARDS. Design First, we performed a systematic review and meta-analysis of
observational studies reporting mortality of critically ill patients with and without ARDS
matched for underlying risk factor. Next, we conducted a survival analysis of prospectively …

Attributable Mortality of Acute Respiratory Distress Syndrome: A Systematic Review, Meta-Analysis, and Observational Study

LK Torres - 2020 - search.proquest.com
Importance: Although acute respiratory distress syndrome (ARDS) is associated with high
mortality, its direct causal link with death is unclear. Clarifying this link is important in order to
justify costly research on prevention of ARDS. Our objective was to estimate the attributable
mortality, if any, of ARDS. Methods: First, we performed a systematic review and meta-
analysis (PROSPERO CRD42017078313) of observational studies reporting mortality of
critically ill patients with and without ARDS matched for underlying risk factor. Next, we …
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