Background Severe combined immunodeficiency (SCID) is a syndrome characterized by
profound T-cell deficiency. BCG vaccine is contraindicated in patients with SCID. Because
most countries encourage BCG vaccination at birth, a high percentage of patients with SCID
are vaccinated before their immune defect is detected. Objectives We sought to describe the
complications and risks associated with BCG vaccination in patients with SCID. Methods An
extensive standardized questionnaire evaluating complications, therapeutics, and outcomes …