One of the main concerns nowadays in the modern world is about waste disposal and byproduct management of the food processing industry. The use of byproducts as bioactive peptides has been extensively studied during recent years as an economically viable way for a waste obtained from one of the most contaminant industries nowadays. In this sense, blood, and collagen, very important byproducts from slaughterhouses and meat industry, have been the most assayed. Despite peptides exerting different bioactivities such as angiotensin I‐converting enzyme (ACE)‐inhibitory, antimicrobial or opioid have been described, studies showing ACE‐inhibitory sequences are the most abundant. Collagen is the most abundant protein in vertebrates and can be easily and cheaply obtained from the meat industry. It is the main constituent of skin, hide, bones, and cartilage, and its nutritional value is very low, because it lacks essential amino acids. The cheapest way to generate bioactive peptides from collagen is through hydrolysis by microorganisms.