Bioactive glass 45S5 powders: effect of synthesis route and resultant surface chemistry and crystallinity on protein adsorption from human plasma

MS Bahniuk, H Pirayesh, HD Singh, JA Nychka… - …, 2012 - pubs.aip.org
Despite its medical applications, the mechanisms responsible for the osseointegration of
bioactive glass (45S5) have yet to be fully understood. Evidence suggests that the strongest
predictor for osseointegration of bioactive glasses, and ceramics, with bone tissue as the
formation of an apatitic calcium phosphate layer atop the implanted material, with
osteoblasts being the main mediator for new bone formation. Most have tried to understand
the formation of this apatitic calcium phosphate layer, and other bioresponses between the …
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