Enzymatic synthesis of aromatic esters of four different sugar alcohols (xylitol, arabitol,
mannitol, and sorbitol) with 3-(4-hydroxyphenyl) propionic acid was performed in organic
solvent medium, using immobilized Candida antarctica lipase (Novozyme 435), and
molecular sieves for control of the water content. The influence of reaction parameters on the
conversion has been investigated, including reaction time, temperature, alcohol/acid molar
ratio, and enzyme amount. The highest conversions (94% for xylitol, 98% for arabitol, 80 …