Biochemical and functional characterization of protein kinase CK2 in ascidian Ciona intestinalis oocytes at fertilization: Cloning and sequence analysis of cDNA for α …

GL Russo, M Tosto, A Mupo, I Castellano… - Journal of Biological …, 2004 - ASBMB
The ubiquitous and pleiotropic dual specificity protein kinase CK2 has been studied and
characterized in many organisms, from yeast to mammals. Generally, the enzyme is
composed of two catalytic (α and/or α′) and two regulatory (β) subunits, forming a
differently assembled tetramer. Although prone to controversial interpretation, the function of
CK2 has been associated with fundamental biological processes such as signal
transduction, cell cycle progression, cell growth, apoptosis, and transcription. Less known is …
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