过去一年中添加的文章，按日期排序
Carbon dots as dual inhibitors of tau and amyloid-beta aggregation for the treatment of Alzheimer's disease
32 天前 - … to effectively cross the blood-brain barrier (BBB) significantly restrains its practicality
as a viable CNS drug candidate. [20] This … practical implications in therapeutic intervention. …
as a viable CNS drug candidate. [20] This … practical implications in therapeutic intervention. …
[HTML][HTML] Blood-brain barrier functions and their impact on pharmacotherapy and pathogenesis of CNS disorders: novel in vitro and translational in vivo studies in …
B Gericke - 2024 - elib.tiho-hannover.de
131 天前 - … relevance of predictive BBB models and CNS disease models for (i) high-throughput
screening of CNS drug … While cell-based in vitro models can offer cost-effective, highly …
screening of CNS drug … While cell-based in vitro models can offer cost-effective, highly …
A Cell-Based Nasal Model for Screening the Deposition, Biocompatibility, and Transport of Aerosolized PLGA Nanoparticles
A Maaz, IS Blagbrough, PA De Bank - Molecular Pharmaceutics, 2024 - ACS Publications
149 天前 - … via aerosolization and the importance of employing ALI cellular models for testing
… drug delivery to the central nervous system (CNS), circumventing the blood–brain barrier …
… drug delivery to the central nervous system (CNS), circumventing the blood–brain barrier …
OPEN ACCESS EDITED BY
D Jane-wit, JY Shao, L Wen, JL McGrath… - Effects of cell …, 2023 - books.google.com
223 天前 - … high degree of translational relevance due to the usage of … factors including blood
brain barrier (BBB) infiltration by blood-… neural networks (CNN) have been developed for pixel …
brain barrier (BBB) infiltration by blood-… neural networks (CNN) have been developed for pixel …
[HTML][HTML] Micro/nanosystems for controllable drug delivery to the brain
223 天前 - … loads across the blood-brain barrier, and the … We also delve into the relevant
diseases, biological barriers, and … US Food and Drug Administration (FDA) for CNS drugs are less …
diseases, biological barriers, and … US Food and Drug Administration (FDA) for CNS drugs are less …
Dual PPAR delta/gamma agonists offer therapeutic potential for Alzheimer's disease
269 天前 - … for their clinical importance for example; PPARα agonists include the fibrates class
of drugs (… approaches have been studied and found successful to predict drug likelihood eg, …
of drugs (… approaches have been studied and found successful to predict drug likelihood eg, …
Utilisation of in vitro and in vivo model systems to investigate complex physiological responses of endothelial cells to stress and stimuli
O Jung - 2023 - ora.ox.ac.uk
342 天前 - … The blood-brain barrier (BBB) continues to present one of the most significant
challenges to the successful development of therapies for central nervous system (CNS) diseases…
challenges to the successful development of therapies for central nervous system (CNS) diseases…