Background Uncertainty persists over the effects of blood pressure lowering in acute
intracerebral haemorrhage. We aimed to combine individual patient-level data from the two
largest randomised controlled trials of blood pressure lowering strategies in patients with
acute intracerebral haemorrhage to determine the strength of associations between key
measures of systolic blood pressure control and safety and efficacy outcomes. Methods We
did a preplanned pooled analysis of individual patient-level data acquired from the main …

Corresponding author: Jun ZHANG doctorzhang_0221@ 163. com who exhibited
treatment-related symptomatic hypotension after administration of antihypertensive drugs,
seemed to continue to be included in the study. Hence, how do we eliminate the related
effects of hypotension (effect on the incidence of adverse events and prognosis)? And if
these effects are not eliminated, should the hypotension-related complications be included
as adverse events? The clinical significance of the study by Moullaali et al. would be greatly …