过去一年中添加的文章,按日期排序

Three-Dimensional Mechanical Microenvironment Rescued the Decline of Osteogenic Differentiation of Old Human Jaw Bone Marrow Mesenchymal Stem Cells

C Hu, Q Yang, X Huang, F Wang… - … Biomaterials Science & …, 2024 - ACS Publications
10 天前 - … that 3D strain microenvironment efficiently rescued the cellular senescence of
old-BMSCs via … bone loss and improving the regeneration of the alveolar bone in the elderly. …

[HTML][HTML] Long non-coding RNA MIAT serves as a biomarker of fragility fracture and promotes fracture healing

C Yu, B Chen, H Su, Y Yang - Journal of Orthopaedic Surgery and …, 2024 - Springer
14 天前 - … , cellular senescence, and osteoclast differentiation. … osteoporosis and 90 patients
with fragility fracture. The diagnosis of osteoporosis was based on the WHO criteria of bone

Hdac3-deficiency increases senescence-associated distention of satellite DNA and telomere-associated foci in osteoprogenitor cells

D Yeo, EL Zars Fisher, S Khosla, JN Farr… - Journal of Bone and …, 2024 - academic.oup.com
15 天前 - … of cellular senescence, which is a zombie-like state 17 associated with increased
marrow fat, bone loss and aging… linked to early cellular senescence alongside the formation of …

The Role of Physiologic Loading, Micronutrient and Trace Mineral Deficiencies and Senescence on Bone Functional Adaptation

N Sekel - 2024 - d-scholarship.pitt.edu
15 天前 - … Conversely, in an ageing population, the full consequence of micronutrient … and
cellular senescence on bone quality remains unknown due to the over reliance of osteoporosis

Inhibition of Mettl3 ameliorates osteoblastic senescence by mitigating m6A modifications on Slc1a5 via Igf2bp2-dependent mechanisms

XW Liu, HW Xu, YY Yi, SB Zhang, SJ Chang… - … et Biophysica Acta (BBA …, 2024 - Elsevier
17 天前 - … the mechanisms of current osteoporosis treatments and bone repair pathophysiology.
… a major role in cellular senescence and is essential for skeletal development and internal …

[HTML][HTML] The current insights of mitochondrial hormesis in the occurrence and treatment of bone and cartilage degeneration

W Da, Q Chen, B Shen - Biological Research, 2024 - Springer
20 天前 - … , and osteoporosis (OP) stand out as significant degenerative diseases affecting bone
and cartilage, with cellular senescence … underpinnings of cellular senescence encompass …

[HTML][HTML] Osteoporosis induced by cellular senescence: A mathematical model

N Siewe, A Friedman - Plos one, 2024 - journals.plos.org
24 天前 - bone loss for men and women during age 50 to 100 years, and the results depend
on the rate η of net formation of senescent cell… , that selectively eliminate senescent cells, and …

Aldo-keto reductase family 1 member A1 contributes to increase the glycolytic metabolism and to accelerate cellular senescence of bone derived mesenchymal stem …

YM Liou, CHAO CHIANG, YIHUI LIN, YUC KAO… - …, 2024 - journals.physiology.org
31 天前 - Skeletal aging characterizes the important event where bone loss is accompanied
by … This event may be due to dysfunctional differentiation of bone derived mesenchymal stem …

Osteocyte ferroptosis induced by ATF3/TFR1 contributes to cortical bone loss during ageing

Y Yin, GJ Chen, C Yang, JJ Wang, JF Peng… - Cell …, 2024 - Wiley Online Library
33 天前 - … of trabecular osteocytes inevitably lead to cellular senescence during ageing.Senescent
cells are susceptible to various modes of cell death, including apoptosis, necroptosis, …

[HTML][HTML] Excess glucose alone depress young mesenchymal stromal/stem cell osteogenesis and mitochondria activity within hours/days via NAD+/SIRT1 axis

BL Yen, LT Wang, HH Wang, CP Hung, PJ Hsu… - Journal of Biomedical …, 2024 - Springer
39 天前 - … its association with bone health and osteoporosis (OP), an age-related disease of
bone fragility with … The cell responsible for bone formation is the osteoblast, a descendant …