过去一年中添加的文章,按日期排序
Astragaloside IV alleviates macrophage senescence and d-galactose-induced bone loss in mice through STING/NF-κB pathway
M Li, Y Niu, L Tian, T Zhang, S Zhou, L Wang… - International …, 2024 - Elsevier
149 天前 - … Cellular senescence plays a critical role in the bone microenvironment during
the development and progression of SOP. Over time, bone marrow mesenchymal stem cells (…
the development and progression of SOP. Over time, bone marrow mesenchymal stem cells (…
NOVEL INSIGHTS FROM THE GUT-JOINT AXIS: MICROBIAL CONTRIBUTION TO SKELETAL HOMEOSTASIS
FS Wang - Orthopaedic Proceedings, 2024 - boneandjoint.org.uk
176 天前 - … senescence, inflammation, oxidative stress, subcellular organelle dysfunction, and
genomic instability as prominent features. Age-… immune responses and cell metabolism. Not …
genomic instability as prominent features. Age-… immune responses and cell metabolism. Not …
Research Progress on the Regulation Mechanism of Aging-related Secretory Phenotype in Osteoporosis
C YANG, G TAN, Z XU - Chinese General Practice - chinagp.net
183 天前 - … feature of cellular senescence and … bone metabolism and inducing bone loss is
very limited. Therefore,this paper discusses the regulatory mechanism of SASP in osteoporosis …
very limited. Therefore,this paper discusses the regulatory mechanism of SASP in osteoporosis …
Cellular Senescence in Periodontitis: From Pathogenesis to Therapeutics
K Rattanaprukskul - 2023 - repository.upenn.edu
186 天前 - … levels of senescence markers within … senescence in the course of periodontitis.
Intriguingly, DQ treatment reduced senescent cell burden and mitigated alveolar bone loss in …
Intriguingly, DQ treatment reduced senescent cell burden and mitigated alveolar bone loss in …
Lipoteichoic acid restrains macrophage senescence via β‐catenin/FOXO1/REDD1 pathway in age‐related osteoporosis
W Cheng, Y Fu, Z Lin, M Huang, Y Chen, Y Hu… - Aging …, 2024 - Wiley Online Library
188 天前 - … role of senescent cells in age-associated bone loss is … causes of cellular senescence
and can adversely affect bone … cellular senescence model to mimic the age-related mice …
and can adversely affect bone … cellular senescence model to mimic the age-related mice …
[HTML][HTML] Differential responses to aging amongst the transcriptome and proteome of mesenchymal progenitor populations
193 天前 - … bone and immune systems 9, 10 , regulating both osteoclast and osteoblast within
the bone … in this study may drive the acceleration of bone loss in aging. The diversity in the …
the bone … in this study may drive the acceleration of bone loss in aging. The diversity in the …
A comparison of bone microarchitectural and transcriptomic changes in murine long bones in response to hindlimb unloading and aging
SJ Meas, GM Daire, MA Friedman, R DeNapoli… - Bone, 2024 - Elsevier
218 天前 - … of bone loss are needed to promote healthy aging. One of the hallmarks of age-related
bone loss is cellular senescence; a … by cell cycle arrest and distinct changes in cellular …
bone loss is cellular senescence; a … by cell cycle arrest and distinct changes in cellular …
USP7 Inhibition Promotes Mesenchymal Stem cell-Macrophage Crosstalk in Age-related Osteoporosis via Efferocytosis and Senolysis
F Zhou, Z Wang, H Li, D Wang, Z Wu, F Bai, Q Wang… - 2023 - europepmc.org
223 天前 - … cellular senescence and … senescent cells caused by USP7 inhibition. In the femurs
and vertebrae of aged mice, it was discovered that USP7 inhibition could rescue bone loss, …
and vertebrae of aged mice, it was discovered that USP7 inhibition could rescue bone loss, …
Cellular senescence in skeletal disease: mechanisms and treatment
X He, W Hu, Y Zhang, M Chen, Y Ding, H Yang… - Cellular & Molecular …, 2023 - Springer
243 天前 - … cellular senescence in bone and bone marrow microenvironments. Targeted SnCs
alleviate age-… pathways participate in the regulation of senescence in age-related bone loss. …
alleviate age-… pathways participate in the regulation of senescence in age-related bone loss. …
[HTML][HTML] Increased deformations are dispensable for cell mechanoresponse in engineered bone analogs mimicking aging bone marrow
AM Regner, M DeLeon, KD Gibbons, S Howard… - bioRxiv, 2023 - ncbi.nlm.nih.gov
244 天前 - … experience bone loss despite rigorous physical activity. Bone mechanoresponse is
in-… Direct delivery of low intensity vibration (LIV) recovers MSC proliferation in senescence …
in-… Direct delivery of low intensity vibration (LIV) recovers MSC proliferation in senescence …