过去一年中添加的文章,按日期排序

Astragaloside IV alleviates macrophage senescence and d-galactose-induced bone loss in mice through STING/NF-κB pathway

M Li, Y Niu, L Tian, T Zhang, S Zhou, L Wang… - International …, 2024 - Elsevier
149 天前 - Cellular senescence plays a critical role in the bone microenvironment during
the development and progression of SOP. Over time, bone marrow mesenchymal stem cells (…

NOVEL INSIGHTS FROM THE GUT-JOINT AXIS: MICROBIAL CONTRIBUTION TO SKELETAL HOMEOSTASIS

FS Wang - Orthopaedic Proceedings, 2024 - boneandjoint.org.uk
176 天前 - senescence, inflammation, oxidative stress, subcellular organelle dysfunction, and
genomic instability as prominent features. Age-… immune responses and cell metabolism. Not …

Research Progress on the Regulation Mechanism of Aging-related Secretory Phenotype in Osteoporosis

C YANG, G TAN, Z XU - Chinese General Practice - chinagp.net
183 天前 - … feature of cellular senescence and … bone metabolism and inducing bone loss is
very limited. Therefore,this paper discusses the regulatory mechanism of SASP in osteoporosis

Cellular Senescence in Periodontitis: From Pathogenesis to Therapeutics

K Rattanaprukskul - 2023 - repository.upenn.edu
186 天前 - … levels of senescence markers within … senescence in the course of periodontitis.
Intriguingly, DQ treatment reduced senescent cell burden and mitigated alveolar bone loss in …

Lipoteichoic acid restrains macrophage senescence via β‐catenin/FOXO1/REDD1 pathway in age‐related osteoporosis

W Cheng, Y Fu, Z Lin, M Huang, Y Chen, Y Hu… - Aging …, 2024 - Wiley Online Library
188 天前 - … role of senescent cells in age-associated bone loss is … causes of cellular senescence
and can adversely affect bonecellular senescence model to mimic the age-related mice …

[HTML][HTML] Differential responses to aging amongst the transcriptome and proteome of mesenchymal progenitor populations

G Duque, J Feehan, N Tripodi, D Kondrikov… - Research …, 2023 - ncbi.nlm.nih.gov
193 天前 - bone and immune systems 9, 10 , regulating both osteoclast and osteoblast within
the bone … in this study may drive the acceleration of bone loss in aging. The diversity in the …

A comparison of bone microarchitectural and transcriptomic changes in murine long bones in response to hindlimb unloading and aging

SJ Meas, GM Daire, MA Friedman, R DeNapoli… - Bone, 2024 - Elsevier
218 天前 - … of bone loss are needed to promote healthy aging. One of the hallmarks of age-related
bone loss is cellular senescence; a … by cell cycle arrest and distinct changes in cellular

USP7 Inhibition Promotes Mesenchymal Stem cell-Macrophage Crosstalk in Age-related Osteoporosis via Efferocytosis and Senolysis

F Zhou, Z Wang, H Li, D Wang, Z Wu, F Bai, Q Wang… - 2023 - europepmc.org
223 天前 - cellular senescence and … senescent cells caused by USP7 inhibition. In the femurs
and vertebrae of aged mice, it was discovered that USP7 inhibition could rescue bone loss, …

Cellular senescence in skeletal disease: mechanisms and treatment

X He, W Hu, Y Zhang, M Chen, Y Ding, H Yang… - Cellular & Molecular …, 2023 - Springer
243 天前 - cellular senescence in bone and bone marrow microenvironments. Targeted SnCs
alleviate age-… pathways participate in the regulation of senescence in age-related bone loss. …

[HTML][HTML] Increased deformations are dispensable for cell mechanoresponse in engineered bone analogs mimicking aging bone marrow

AM Regner, M DeLeon, KD Gibbons, S Howard… - bioRxiv, 2023 - ncbi.nlm.nih.gov
244 天前 - … experience bone loss despite rigorous physical activity. Bone mechanoresponse is
in-… Direct delivery of low intensity vibration (LIV) recovers MSC proliferation in senescence