Bone morphogenetic protein 7 in dormancy and metastasis of prostate cancer stem-like cells in bone

A Kobayashi, H Okuda, F Xing, PR Pandey… - Journal of Experimental …, 2011 - rupress.org
… (bone morphogenetic protein 7) secreted from bone stromal cells induces senescence in
prostate cancer stem-like cells (… -activated protein kinase and increasing expression of the cell

Bone secreted factors induce cellular quiescence in prostate cancer cells

LY Yu-Lee, YC Lee, J Pan, SC Lin, T Pan, G Yu… - Scientific reports, 2019 - nature.com
… disseminated tumor cells (DTCs) had been dormant at the metastatic site in bone 3 . Tumor
… looked for additional bone secreted factors that promote cellular dormancy of PCa cells. We …

[HTML][HTML] Interaction between prostate cancer stem cells and bone microenvironment regulates prostate cancer bone metastasis and treatment resistance

L Yao, X Zhang - Journal of Cancer, 2022 - ncbi.nlm.nih.gov
… matrix, including insulin-like growth factors (IGFs), bone morphogenetic proteins (BMPs), …
of bone prostate cancer bone metastasis, and how to accurately discriminate the dormant

Secreted protein acidic and rich in cysteine (SPARC) mediates metastatic dormancy of prostate cancer in bone

S Sharma, F Xing, Y Liu, K Wu, N Said… - Journal of Biological …, 2016 - ASBMB
… vivo selection by implanting PC3mm stem-like cells into tibial bones. We found that indolent
dormant state of cancer cells by stimulating the secretion of bone morphogenetic protein 7 (…

Bone metastasis: molecular mechanisms implicated in tumour cell dormancy in breast and prostate cancer

L Quayle, PD Ottewell, I Holen - Current cancer drug targets, 2015 - ingentaconnect.com
bone morphogenetic protein receptor type II (BMPR2). The increased expression of NDRG1,
an apparent effector in BMP7-mediated dormancy… In this study, stem-like breast cancer cells

ROLE OF SPARC IN DORMANCY OF PROSTATE CANCER IN THE BONE

S Sharma - 2016 - wakespace.lib.wfu.edu
Metastasis of prostate cancer cells to the bone is known to be … phenotype of prostate cancer
stem like cells by inducing … by stimulating the secretion of bone morphogenetic protein 7

Interactions between cancer cells and bone microenvironment promote bone metastasis in prostate cancer

X Zhang - Cancer communications, 2019 - Springer
… that bone morphogenetic protein 7 (BMP7) promotes metastatic cancer cell dormancy by …
TGF-β2 was found to induce dormancy of disseminated prostate cancer cells through …

Wnt and β-catenin signaling in the bone metastasis of prostate cancer

Z Kaplan, SP Zielske, KG Ibrahim, FC Cackowski - Life, 2021 - mdpi.com
… in the bone, including migration, phenotypic plasticity, dormancy and … For example, cancer
stem-like cells have overlapping … (EMT) cells, and dormant disseminated tumor cells often …

Abstract C92: Bone morphogenetic protein 7 regulates dormancy and recurrence of prostate cancer stem cell in bone

A Kobayashi, F Xing, H Okuda, PR Pandey, S Pai… - Cancer Research, 2013 - AACR
… of cancer stem-like cells for dormancy and recurrence in bone metastasis of prostate cancer.
… a critical role in the regulation of dormancy and recurrence of prostate tumor cells in bone

Osteoblasts and osteoclasts: an important switch of tumour cell dormancy during bone metastasis

R Dai, M Liu, X Xiang, Z Xi, H Xu - … of Experimental & Clinical Cancer …, 2022 - Springer
… , bone morphogenetic protein 7 (BMP7) secreted by osteoblasts induced the dormancy of
PC-3 prostate cancer cells … induced metastatic growth of stem-like prostate cancer cells in the …