… and cellular views of bone remodelling turn to be helpful (i) to better understand the blurry
synergy between mechanical and metabolic factors triggering bone remodelling, both in …

… Bone remodelling, as many biological phenomena, is inherently multi-scale, ie it is … and the
BioShape 3D spatial simulator respectively (i) for describing the bone remodelling process in …

… To fulfil this objective we firstly introduce, in Section 4, bone remodelling (BR), a well-known
inherently MS biological phenomenon. Then, we use both CxA (Section 5) and …

… the bone implant requires on one side the complex geometry that should be congruent to the
free form of a bio-shape… In accordance to the regular procedure for remodelling of bone and …

… 5 A case study: the bone remodelling process As a case study, we take into account the bone
remodelling. In the following, we formulate a MS model of the process respectively in terms …

… To ease the import of Shape Calculus models in BioShape, the … BioShape is applied to the
bone remodelling process, a … In a healthy individual, remodelling does not alter the global …

… Social and Clinical Relevance A better understanding of the bone remodelling process
and of how it is influenced in these and other diseases has social and clinical relevance. …

… Bone possesses the intrinsic capacity for regeneration and remodelling, being bone
remodelling the biological process whereby living bone tissue renews itself in the course of life. …

… scheme, has been first defined for describing bone remodelling and then executed in
BIOSHAPE 3. In particular, the possibility in BIOSHAPE to associate to each shape its own physical …

… the bone matrix through a network of canaliculi. As we can see, the bone remodelling process
… All the involved entities can be modelled in terms of BIOSHAPE shapes. In particular, we …