4 天前 - … brain health. In this review, we investigate the intricate relationship between the
AGE-RAGE pathway and brain aging in … Reduction of AGE deposition in brain tissue either …

20 天前 - … increased risk of various diseases such as metabolic syndrome, cancers,
neurodegenerative disorders, and cardiovascular diseases. Aging is currently believed to be due to …

21 天前 - … My analysis shows that the ApoE4 allele shifts the brain metabolism towards lipid
… of brain tissue samples from healthy human subjects between 33-50 years of age carrying …

23 天前 - … examining their interplay with cerebral glucose metabolism, a predictor … cerebral
glucose metabolism, subclinical atherosclerosis and cardiovascular risk factors in middle-aged …

23 天前 - … lifespans, neurons have altered metabolism and are subjected to age-related changes
that … Accessibility to living brains for studies of neuronal metabolism is limited, so in vitro …

23 天前 - … petuate brain inflammation and cognitive deterioration in aging … Furthermore, we
highlight the role of CP metabolism in … CP metabolism could be effective in safeguarding brain …

25 天前 - … tool for assessing cerebral glucose metabolism in AD, while in vivo 1H-nuclear
magnetic resonance (MR) spectroscopy can also measure brain metabolism in humans, …

28 天前 - … By affecting redox systems, neurotransmitter and glucose metabolism, calcium
signaling… , as well as contribute to neurodegenerative diseases. Among brain cells, glia account …

31 天前 - … has associated APOE with other neurodegenerative proteinopathies and broader
ageing-related brain changes, such as neuroinflammation, energy metabolism failure, loss of …

33 天前 - … can be utilized to investigate the mechanisms of brain aging and may present new
avenues for discovering innovative therapeutic approaches for neurodegenerative diseases. …