… C3 glomerulopathy histologic index and the risk of kidney failure in a multicenter cohort of 111
patients with C3 glomerulopathy … previously proposed C3 glomerulopathy histologic index …

In both atypical hemolytic uremic syndrome (aHUS) and C3 glomerulopathy (C3G) complement
plays a primary role in disease pathogenesis. Herein we report the outcome of a 2015 …

… For the assessment of the discriminative capability of the longitudinal change in proteinuria
in C3 glomerulopathy, we focused on the time interval between 6 months and 5 years, and a …

… To analyze the outcomes of C3-glomerulopathy (C3-GP) and … patients with newly diagnosed
C3-GP (with primary C3-GP – … morphological presentation of C3 glomerulopathy: a single-…

… /C3 glomerulopathy (C3G). … C3 glomerulopathies. Mutations in the factor H (FH) gene
causing very low FH levels or impaired FH cofactor activity, or C3 nephritic factor (C3NeF) and C3 …

… Direct immunofluorescence stainings will be positive to immunoglobulins, mainly IgG and
IgM, as well as C3 and/or C1. C3 glomerulopathy is produced by dysfunction of the alternative …

… C3 glomerulopathy as an ancillary diagnostic tool. All biopsies from patients diagnosed with
C3 glomerulopathy in … included (n = 14; 10 C3 glomerulonephritis, 4 dense deposit disease). …

… , such as C3 glomerulopathies (C3Gs). Complement is frequently overactivated by C3
nephritic factors (C3NeFs). C3NeFs bind to a neoepitope on the AP C3 convertase, C3bBb, …

… Conclusions: Drusen are common in forms of C3 glomerulopathy caused by compound …
Individuals with a C3 glomerulopathy should be assessed ophthalmologically at diagnosis, …

… C3 glomerulopathy (C3G) is a rare glomerular disease driven by complement
dysregulation with high post-transplantation recurrence rates. Its treatment is mainly based on …