过去一年中添加的文章,按日期排序

Chemokines and Cytokines in Immunotherapy of Melanoma and Other Tumors: From Biomarkers to Therapeutic Targets

R Reschke, AH Enk, JC Hassel - International Journal of Molecular …, 2024 - mdpi.com
5 天前 - … such as CCR2, CCR4 or Il-6R can reduce the recruitment of tumor-associated …
target these chemokines and cytokines have the potential to personalize cancer immunotherapy

[HTML][HTML] Interactions between LAMP3+ dendritic cells and T-cell subpopulations promote immune evasion in papillary thyroid carcinoma

Z Wang, X Ji, Y Zhang, F Yang, H Su… - … for Immunotherapy of …, 2024 - ncbi.nlm.nih.gov
19 天前 - … has been applied in clinical practice, its therapeutic efficacy … remodeling and
exploration of novel treatment targets. … CCL17-CCR4, CCL5-CCR4, and CCL22-CCR4, and …

Side effects of dermato-oncologic therapies

JC Hassel, L Zimmer - Dermatologie (Heidelberg, Germany), 2024 - europepmc.org
23 天前 - Background Immune checkpoint inhibitors (ICIs) such as PD (L) 1 and CTLA4
antibodies as well as targeted therapies such as BRAF and MEK inhibitors have significantly …

Arzneimittelexantheme unter Immun-und zielgerichteter onkologischer Therapie

M Ziemer, E Livingstone - Die Dermatologie, 2024 - Springer
28 天前 - … Aufgrund der hohen Expression von CCR4 auf malignen T‑Zellen bei der Mycosis
fungoides und dem Sézary-Syndrom kann dieser Rezeptor als therapeutisches Ziel genutzt …

Drug-related exanthema under immunotherapy and targeted oncological therapy

M Ziemer, E Livingstone - Dermatologie (Heidelberg, Germany), 2024 - europepmc.org
29 天前 - … Cutaneous side effects are common across all drug classes and … drug class, many
exanthemas can occur with both oncological immunotherapies and various targeted therapies

Pan-cancer and single-cell analyses reveal LAMP3 as a biomarker associated with cancer prognosis and immune infiltration

CF Wang, X Sun, H Tang, DH Guo - 2024 - researchsquare.com
50 天前 - tumor tissue through CCL17-CCR4 and CCL22-CCR4. … potential targets for cancer
immunotherapeutic therapies … immune cells into the tumor microenvironment. We analyzed …

… 2 study of oral CCR4 antagonist FLX475 (tivumecirnon) plus pembrolizumab in subjects with head and neck squamous cell carcinoma (HNSCC) previously treated …

J Muzaffar, K Kirtane, R Redman, MH Yang, TM Kim… - Cancer Research, 2024 - AACR
74 天前 - CCR4 antagonist designed to block the recruitment of immunosuppressive regulatory
T cells (T reg ) into the tumor … with pembrolizumab in subjects with advanced cancer. Early …

Abstract LB130: Identification of fully human CCR8 antibodies that demonstrate excellent ADCC function, potent blocking activity, and robust anti-tumor immune …

H Liang, Y Guo, M Yin, A Kawagishi, T Terada… - Cancer Research, 2024 - AACR
74 天前 - … ADCC function, strong blocking activity, and superior in vivo anti-tumor activity,
which may support further development into a novel cancer immunotherapy targeting Tregs. …

A novel CCR4 antagonist induces potent anti-tumor response through inhibition of Treg migration into the tumor microenvironment

R Nair, C Abbineni, KC Talluri, AA Dhudashiya, A AB… - Cancer Research, 2024 - AACR
88 天前 - CCR4 expression is associated with poor prognosis in various solid tumors. This …
the therapeutic targeting of CCR4-expressing Tregs to enable effective and durable anti-tumor

[引用][C] Targeting Other Promising Cell Surface Receptors: ROR1, CD38, CD25, and CCR4

M Wang - Precision Cancer Therapies vol 2‐Immunologic …, 2024 - Wiley Online Library
119 天前 - … or solid cancers. This discovery of onco-embryonic expression soon attracted
research attention directed toward therapeutic targeting in patients with ROR1-expressing cancer. …