… to treat chronic cerebrospinal venous insufficiency (CCSVI), a vascular condition reportedly
… Despite this, the use of PTA to alleviate CCSVI in MS patients remains controversial [9, 10]. …

… of patients with CCSVI had … CCSVI patients with confirmed autoimmune disease or
suspected/subclinical autoimmune disease and provided comprehensive clinical features of CCSVI …

… The aim of this study is to search the literature and study the correlation of MS with CCSVI,
comparing the incidence of CCSVI in patients with MS against control groups, and also to …

… cerebrospinous venous insufficiency (CCSVI) associated … to conduct randomised double
blinded controlled trials (RCTs… One of the key issues in this debate is whether an unplanned …

… that led to the description of CCSVI as well as the conceptual and … and the interpreting
physician were blinded to the diagnosis, … as a key feature of MS pathology (25). The contribution of …

… of CCSVI in multiple sclerosis and in other neurodegenerative diseases, an un-blinded, …
The authors independently selected key points from the two PIS on which to develop the …

… of CCSVI in MS questioning the concept of CCSVI as the … A standardized technique, rigorous
blinding and quality … endothelial functioning are often also key players in vascular-immune …

… color Doppler ultrasound of the IJVs in accordance with the recommendations of the
international consensus conference on the use of color Doppler ultrasound in patients with CCSVI.…

… CCSVI on the other, calls for further exploration on a wider number of patients. The impact of
CCSVI … Clinical evaluation and EDSS score were assessed by a single neurologist blind to …

… This however is comparable with the improvement seen with placebos in published double-blind
controlled trials of MS therapy. Subsequent investigators have been unable to replicate …