… Recent evidence, however, demonstrates the existence and functional participation of
alternative receptors. Here, we will review the functional role of CD40L and its receptors in …

… receptor only for atherothrombosis as indicated by a reduction of thrombus‐ and injury‐induced
lesion growth in a wire injury model in animals with platelet‐specific CD40L … To update …

… CD40-CD40L pathway is an attractive therapeutic target to reduce clinical complications of
atherosclerosis. The CD40-CD40L … their presence on T-cells and APCs, CD40 and CD40L …

… express CD40 ligand (CD40L), which is then cleaved and released as soluble CD40 ligand
(sCD40L). The sCD40L binds to circulating monocytes through both its receptor CD40 and …

… First, the tumor necrosis factor homology domain allows for binding to its receptor, CD40. …
, allows for its binding to glycoprotein (GP) IIb/IIIa. Third, the trimeric structure of CD40L and of …

… indicate that the cleaved CD40L can interact with a different counter-receptor in both mouse
… CD40 and CD40L under conditions relevant for atherosclerosis and atherothrombosis, we …

… (TNF)-receptor-related signalling molecule CD40 and its ligand CD40L have been shown to
… on platelets contributes to thrombus formation and atherothrombosis, possibly independent …

… The co-stimulatory molecule CD40 and its ligand CD40L (… CD40-CD40L dyad in
atherosclerosis, and we discuss recent studies on the therapeutic potential of novel CD40-CD40L …

… receptor CD40 and its counterpart CD40 ligand (CD40L, recently renamed CD154) considered
their … the in vivo location of SDF-1 and its receptor CXCR-4 (modulated by CD40 signaling…

… Interestingly, platelets also express substantial levels of the alleged counter-receptor for
CD40L, ie, CD40, 40,41 but its role has only been summarily described and suggests a role in …