过去一年中添加的文章，按日期排序
Pharmacotherapy for osteoarthritis-related pain: current and emerging therapies
M Zhang, Z Wang, C Ding - Expert Opinion on Pharmacotherapy, 2024 - Taylor & Francis
3 天前 - … Clinical research has reported serum CGRP … CGRP antagonists have been
demonstrated the significant clinical benefits for migraine [Citation181]. Galcanezumab (a CGRP …
demonstrated the significant clinical benefits for migraine [Citation181]. Galcanezumab (a CGRP …
Sensory ASIC3 channel exacerbates psoriatic inflammation via a neurogenic pathway in female mice
C Huang, PY Sun, Y Jiang, Y Liu, Z Liu, SL Han… - Nature …, 2024 - nature.com
9 天前 - … (CGRP) from sensory neurons to promote neurogenic inflammation. Botulinum
neurotoxin A and CGRP antagonists … In contrast, replenishing CGRP in the skin of Asic3 KO mice …
neurotoxin A and CGRP antagonists … In contrast, replenishing CGRP in the skin of Asic3 KO mice …
Provocation of attacks to discover migraine signaling mechanisms and new drug targets: early history and future perspectives-a narrative review
J Olesen - The Journal of Headache and Pain, 2024 - Springer
10 天前 - … Calcitonin gene-related peptide (CGRP) did the same, supporting the development
of CGRP antagonists now widely used in patients. Likewise, pituitary adenylate cyclase …
of CGRP antagonists now widely used in patients. Likewise, pituitary adenylate cyclase …
Aromatase inhibitors evoke periorbital allodynia in mice via calcitonin gene-related peptide and its receptors in Schwann cells
M Marini, DSM de Araujo, M Chieca… - Confinia …, 2024 - confiniacephalalgica.com
12 天前 - … antagonist (A967079) or a CGRP receptor antagonist (… known to promote PMA by
CGRP action in Schwann cells, … nerve terminals, releases CGRP that engages its receptor in …
CGRP action in Schwann cells, … nerve terminals, releases CGRP that engages its receptor in …
Nociceptive adenosine A2A receptor on trigeminal nerves orchestrates CGRP release to regulate the progression of oral squamous cell carcinoma
L Jiang, Y Zhou, S Tang, D Yang, Y Zhang… - International Journal of …, 2024 - nature.com
12 天前 - … We fed tumor-bearing mice with rimegepant, a CGRP receptor antagonist which
induced a significant reduction in tumor volume (Fig. 4a). Histological analysis verified this …
induced a significant reduction in tumor volume (Fig. 4a). Histological analysis verified this …
The preclinical discovery and development of atogepant for migraine prophylaxis
C Baraldi, D Beier, P Martelletti… - Expert Opinion on Drug …, 2024 - Taylor & Francis
19 天前 - … This review centers its attention on atogepant, a potent CGRP receptor antagonist
that is approved for migraine prophylaxis in adults with episodic and chronic migraine […
that is approved for migraine prophylaxis in adults with episodic and chronic migraine […
Development of sustainable processes for API production
G Vinciarelli - 2024 - usiena-air.unisi.it
22 天前 - … of fezolinetant, a selective NK3 receptor antagonist, is described. The synthetic
strategies … intermediate of rimegepant, an oral CGRP antagonist for the treatment of migraine, …
strategies … intermediate of rimegepant, an oral CGRP antagonist for the treatment of migraine, …
Gepoolte Analyse zu Zavegepant-Nasenspray
T M. Heim - DNP–Die Neurologie & Psychiatrie, 2024 - Springer
26 天前 - … Der kleinmolekulare intranasal applizierbare CGRP-Rezeptorantagonist Zavegepant
… belastenden Symptoms erwies sich der CGRP-Antagonist als signifikant wirksamer im …
… belastenden Symptoms erwies sich der CGRP-Antagonist als signifikant wirksamer im …
Intervening in the Premonitory Phase to Prevent Migraine: Prospects for Pharmacotherapy
N Karsan, PJ Goadsby - CNS drugs, 2024 - Springer
29 天前 - … The emergence of novel targeted migraine treatments more recently, specifically
calcitonin gene-related peptide (CGRP) receptor antagonists (gepants), has reignited interest …
calcitonin gene-related peptide (CGRP) receptor antagonists (gepants), has reignited interest …
The evolving landscape and research trend of calcitonin gene-related peptide in migraine: a bibliometric analysis and visualization
L Wang, Q Wang, H Diao, X Liu, Y Zhao - Frontiers in Neurology - frontiersin.org
30 天前 - … CGRP receptor antagonists and monoclonal antibodies that target CGRP or its …
Future research should target identifying critical therapeutic targets in CGRP antagonist …
Future research should target identifying critical therapeutic targets in CGRP antagonist …