[HTML][HTML] COVID-19: combining antiviral and anti-inflammatory treatments

J Stebbing, A Phelan, I Griffin, C Tucker… - The Lancet Infectious …, 2020 - thelancet.com
… used to treating rheumatoid arthritis with Janus kinase (JAK) inhibitors and working in an
area (Lombardy, Italy) with a high incidence of coronavirus disease 2019 (COVID-19), we read …

[HTML][HTML] Combining antivirals and immunomodulators to fight COVID-19

V Feuillet, B Canard, A Trautmann - Trends in immunology, 2021 - cell.com
… , we propose combining: (i) the development of efficient antivirals administered early …
anti-inflammatory treatments when needed, but not too early to interfere with endogenous antiviral

Union is strength: antiviral and anti-inflammatory drugs for COVID-19

JJ Naveja, A Madariaga-Mazon, F Flores-Murrieta… - Drug discovery today, 2021 - Elsevier
… of drugs, focusing on patients moderately ill with COVID-19, and propose drug products,
including … Here, we present a strategy combining molecular docking vs with practical and clinical …

The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from …

W Zhang, Y Zhao, F Zhang, Q Wang, T Li, Z Liu… - Clinical …, 2020 - Elsevier
… pneumonia (COVID-19) patients treated with ruxolitinib in combination with … and anti-inflammatory
effects, the benefit in treating COVID-19 may be mainly attributed to its anti-viral effects…

[HTML][HTML] Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment

M Soy, G Keser, P Atagündüz, F Tabak… - Clinical …, 2020 - Springer
… in COVID-19. Once, immunologic complications like cytokine storm occur… anti-viral treatment
alone is not enough and should be combined with appropriate anti-inflammatory treatment

Combination therapies for COVID19: An overview of the clinical trials landscape

S Akinbolade, D Coughlan, R Fairbairn… - British journal of …, 2022 - Wiley Online Library
COVID-19 clinical trials are testing combination therapies, with … combination pivotal
trials, of which approximately 60% are exploring drug classes such as antivirals and anti-inflammatory

Antiviral and antiinflammatory treatment with multifunctional alveolar macrophage‐like nanoparticles in a surrogate mouse model of COVID19

B Li, W Wang, W Song, Z Zhao, Q Tan… - Advanced …, 2021 - Wiley Online Library
… Multifunctional AM-like NPs (termed TN@AM NPs) were successfully fabricated for combined
antiviral and anti-inflammatory treatments in a surrogate disease of COVID-19 caused by …

Current pharmacological treatments for COVID19: What's next?

C Scavone, S Brusco, M Bertini… - British journal of …, 2020 - Wiley Online Library
drugs administered to patients with COVID-19, focusing on their antiviral, immune-modulatory
and/or anti-inflammatory … of the combination lopinavir/ritonavir in patients with COVID-19 is …

[HTML][HTML] Immune therapy, or antiviral therapy, or both for COVID-19: a systematic review

F Cantini, D Goletti, L Petrone, S Najafi Fard, L Niccoli… - Drugs, 2020 - Springer
… for COVID-19 may be a three-step combination therapy, … stage of the disease, and combined
dexamethasone 6 mg/day plus … of anti-inflammatory and immune therapies in COVID-19: …

Repurposing of anticancer drugs expands possibilities for antiviral and anti-inflammatory discovery in COVID-19

M Aldea, JM Michot, FX Danlos, A Ribas, JC Soria - Cancer Discovery, 2021 - AACR
… Also, camostat mesylate, a direct TMPRSS2 inhibitor, is currently being investigated in
several clinical trials for COVID-19 as monotherapy or in combination with bicalutamide, with the …